Ghmp kinase family protein

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August undefined, 2024

WebProtein Family Annotation; Gene Product Annotation; Domain Annotation: SCOP/SCOPe Classification SCOP Database Homepage. Chains Domain Info Class Fold Superfamily Family ... GHMP Kinase, C-terminal domain (From Topology) T: GHMP Kinase, C-terminal domain: F: GHMP_kinases_C: ECOD (1.6) Domain Annotation: CATH CATH Database … WebProtein: KIME_HUMAN Mevalonate kinase. FUNCTION: May be a regulatory site in cholesterol biosynthetic pathway. CATALYTIC ACTIVITY: ATP + (R)-mevalonate = ADP + (R)-5- phosphomevalonate. ... SIMILARITY: Belongs to the GHMP kinase family. Mevalonate kinase subfamily. SEQUENCE CAUTION: Sequence=CAA53059.1; …

GALE protein (human) - STRING interaction network

WebProtein name Protein family Gene symbol Gene ID Organism Score Rank [1] Untitled. ... Mevalonate kinase (MK) (EC 2.7.1.36) GHMP kinase family, Mevalonate kinase subfamily: MVK: 4598; Homo sapiens (Human) 2.2336: 7: P16233: Pancreatic triacylglycerol lipase (PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3) WebDec 1, 2000 · The crystal structure of homoserine kinase and its complex with ADP is the first to shed light on the fold and the catalytic site of GHMP class kinases. It illustrates a novel nucleotide binding mechanism. In particular, a distinct glycine-rich loop is used in phosphate binding, and the interactions between protein and nucleotide result in an ... how to solve poor roads using physics

Structure of the Ternary Complex of Phosphomevalonate …

WebAlthough related to GHMP kinase, its mode of action remains unclear. Structure. The protein adopts a secondary structure consisting of five alpha helices and six antiparallel … http://pfam-legacy.xfam.org/family/PF09109 WebN-acetylgalactosamine kinase; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates; Belongs to the GHMP kinase family. GalK subfamily how to solve postfix expression

197258 - Gene ResultFCSK fucose kinase [ (human)] - National …

GHMP kinase, N-terminal domain protein …

WebMevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. WebNov 20, 2024 · The GHMP (galactokinase, homoserine kinase, mevalonate kinase and phosphomevalonate kinase) kinase gene superfamily is a unique class of ATP … how to solve potential security risk aheadWebJun 1, 2001 · This entry describes 2 isoforms produced by Alternative splicing.. Q9C6T1-1. This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of … novel highboard

"WebProtein target information for GHMP kinase, N-terminal domain protein (Faecalibacterium prausnitzii A2-165). Find diseases associated with this biological target and compounds … " - Ghmp kinase family protein

Ghmp kinase family protein

Structure of the Methanococcus jannaschii Mevalonate Kinase, a …

WebGHMP kinase family protein; Sugar-1-kinase with a strict substrate specificity for D-glucuronic acid and ATP. Involved in the biosynthesis of UDP- glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell- wall polymers. May be also involved in a salvage pathway for glucuronic acid (By similarity) WebThe GHMP kinases are a structurally related family of small molecule kinases named after four of its members - galactokinase, homoserine kinase, mevalonate kinase and …

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WebIn molecular biology, the GHMP kinase family is a family of kinase enzymes. Members of this family include homoserine kinases EC 2.7.1.39, galactokinases EC 2.7.1.6, and … Webresolution unexpectedly reveals that xol-1 encodes a GHMP kinase family member, despite sequence identity of 10% or less. Because GHMP kinases, thus far, have only been characterized as small molecule kinases involved in metabolic pathways, for example, amino acid and cholesterol synthesis, XOL-1 is the first member that controls …

WebMevalonate/galactokinase family protein. GeneRIFs: Gene References Into Functions. important role during phosphate deprivation through interaction with mannose-rich glycans of PAP26-S2; ... galacturonic acid-1-phosphate kinase is a new member of the GHMP kinase superfamily in plants. [galacturonic acid-1-phosphate kinase] WebBelongs to the GHMP kinase family. IspE ... Family and domain databases. Gene3D. 3.30.230.10 1 hit; 3.30.70.890 1 hit; HAMAP. MF_00061 IspE 1 hit; InterPro. View protein in InterPro; IPR013750 GHMP_kinase_C_dom; IPR036554 GHMP ... View protein in Pfam; PF08544 GHMP_kinases_C 1 hit; PF00288 GHMP_kinases_N 1 hit; SUPFAM. …

WebMar 15, 2002 · Analysis of the MVK model in the context of the other members of the GHMP kinase family offers the opportunity to understand both the mechanism of these …

WebThe galacto-, homoserine-, mevalonate-, phosphomevalonate-kinase (GHMP) superfamily encompases a wide-range of protein function. Three members of the family …

WebFeb 1, 2007 · The GHMP kinases which in 1993 firstly identified by protein sequence alignment in the form of sugar kinase (Bork et al. 1993; Timson 2007) are a structurally … how to solve poor communication in workplaceWebThe SCOP classification for the GHMP Kinase, C-terminal domain superfamily including the families contained in it. Additional information provided includes InterPro annotation (if available), Functional annotation, and SUPERFAMILY links to genome assignments, alignments, domain combinations, taxonomic visualisation and hidden Markov model … novel hildaWebPhosphomevalonate kinase, peroxisomal; GHMP kinase family protein; Its function is described as kinase activity, ATP binding; Involved in phosphorylation; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains: Phosphomevalonate kinase, eukaryotic (InterPro:IPR005916), … how to solve poptropica timmy failureWebprotein_coding: Description : GHMP kinase family protein;(source:Araport11) Chromosome : 1: Locus : AT1G31910 (Note: use this locus link to see all functional annotations, associated gene models, markers and ESTs). Map Detail Image : Center on AT1G31910.1 Full-screen view novel home healthWebJul 28, 2024 · Due to high mobility in these motifs, very high levels of B factors are often recorded not only in HSK but also in other members of GHMP Kinase family members [65, 68,69,70]. Krishna et al. [ 53 ] proposed that the closed state of an enzyme is maintained by an effective salt bridge formed between Arg-187 and Asp-23 in crystallographic studies ... novel hesperadinWebMitogen-activated protein kinases (MAPKs) are important components of the tripartite mitogen-activated protein kinase signaling cascade and play an important role in plant growth and development. Although members of the MAPK gene family have been identified in model plants, little information is available regarding this gene family in fruit crops. novel home care agencyWebDec 5, 2024 · The At5g14470 locus encodes a putative kinase from the GHMP kinase family, recently named AtGlcAK2 or glucuronokinase 2 and formerly known as AtGALK2 or galactokinase 2. However, because of unclarities in the current annotation and its primary function prediction, we propose to rename it to A H L -Pr i ming Protein 1 (ALI1). how to solve power factor